Single‑ and multi‑trait genomic prediction and genome‑wide association analysis of grain yield and micronutrient‑related traits in ICARDA wheat under drought environment

Published Date
October 18, 2023
Type
Journal Article
Single‑ and multi‑trait genomic prediction and genome‑wide association analysis of grain yield and micronutrient‑related traits  in ICARDA wheat under drought environment
Authors:
Wuletaw Tadesse
EL Gataa Zakaria, Fatima Ezzahra Rachdad, Adil El-Baouchi, Zakaria Kehel, Admas Alemu

Globally, over 2 billion people sufer from malnutrition due to inadequate intake of micronutrients. Genomic-assisted
breeding is identifed as a valuable method to facilitate developing new improved plant varieties targeting grain yield
and micronutrient-related traits. In this study, a genome-wide association study (GWAS) and single- and multi-trait-based
genomic prediction (GP) analysis was conducted using a set of 252 elite wheat genotypes from the International Center
for Agricultural Research in Dry Areas (ICARDA). The objective was to identify linked SNP markers, putative candidate
genes and to evaluate the genomic estimated breeding values (GEBVs) of grain yield and micronutrient-related traits.. For
this purpose, a feld trial was conducted at a drought-prone station, Merchouch, Morocco for 2 consecutive years (2018 and
2019) followed by GWAS and genomic prediction analysis with 10,173 quality SNP markers. The studied genotypes exhibited a signifcant genotypic variation in grain yield and micronutrient-related traits. The GWAS analysis identifed highly
signifcantly associated markers and linked putative genes on chromosomes 1B and 2B for zinc (Zn) and iron (Fe) contents,
respectively. The genomic predictive ability of selenium (Se) and Fe traits with the multi-trait-based GP GBLUP model was
0.161 and 0.259 improving by 6.62 and 4.44%, respectively, compared to the corresponding single-trait-based models. The identifed signifcantly linked SNP markers, associated putative genes, and developed GP models could potentially facilitate breeding programs targeting to improve the overall genetic gain of wheat breeding for grain yield and biofortifcation of micronutrients via marker-assisted (MAS) and genomic selection (GS) methods

Citation:
Wuletaw Tadesse, EL Gataa Zakaria, Fatima Ezzahra Rachdad, Adil El-Baouchi, Zakaria Kehel, Admas Alemu. (18/10/2023). Single‑ and multi‑trait genomic prediction and genome‑wide association analysis of grain yield and micronutrient‑related traits in ICARDA wheat under drought environment. Molecular Genetics and Genomics.
Keywords:
multi-trait genomic prediction
gwas
bread wheat
micronutrients