Identification of novel proteomic biomarkers for hypertension: a targeted approach for precision medicine
Background Hypertension is a critical public health issue worldwide. The identification of specific proteomic biomarkers in the Qatari population aims to advance personalized treatment strategies. Methods We conducted proteomic profiling on 778...
Selection Increases Mitonuclear DNA Discordance but Reconciles Incompatibility in African Cattle
Mitochondrial function relies on the coordinated interactions between genes in the mitochondrial DNA and nuclear genomes. Imperfect interactions following mitonuclear incompatibility may lead to reduced fitness. Mitochondrial DNA introgressions...
Dynamics of multiple sustainable agricultural intensification practices adoption: Application of the intertemporal multivariate probit model
Applying an intertemporal multivariate probit model, we reveal complex complementarity and substitution effects as well as new insights on the drivers of adopting input-intensive and natural resource management (NRM) practices in rural Ethiopia...
Genome-wide association study reveals major loci for resistance to septoria tritici blotch in a Tunisian durum wheat collection
Septoria tritici blotch (STB) is a devastating fungal disease affecting durum and bread wheat worldwide. Tunisian durum wheat landraces are reported to be valuable genetic resources for resistance to STB and should prominently be deployed in...
Detection and Partial Characterization of Polerovirus and Luteovirus Isolates Associated With Lentil and Chickpea in Ethiopia
The partial nucleotide sequence of the coat protein (CP) gene of Ethiopian isolates of chickpea chlorotic stunt virus (CpCSV, genus Polerovirus), beet western yellows virus (BWYV, genus Polerovirus), and soybean dwarf virus (SbDV, genus...
Boosting photosynthesis opens new opportunities for agriculture sustainability and circular economy: The BEST-CROP research and innovation action
There is a need for ground-breaking technologies to boost crop yield, both grains and biomass, and their processing into economically competitive materials. Novel cereals with enhanced photosynthesis and assimilation of greenhouse gasses, such...
A Blueprint for Building Resilience and Food Security in MENA and SSA Drylands: Diversifying Agriculture With Neglected and Underutilized Species
Drylands, encompassing 41% of global land and supporting over 2 billion people, face significant challenges, including water scarcity, extreme temperatures, and soil degradation. Dryland spans vast areas of Middle East and North Africa (MENA)...
Genome-wide scans for signatures of selection in North African sheep reveals differentially selected regions between fat- and thin-tailed breeds
North Africa counts several sheep breeds that can be categorized as fat- and thin-tailed. The former are well adapted to dryland environments. In this study, we used 50K genome-wide single nucleotide polymorphism profiles from 462 animals...
History and genetic diversity of African sheep: Contrastingphenotypic and genomic diversity
Domesticated sheep have adapted to contrasting and extreme environmentsand continue to play important roles in local community-based economiesthroughout Africa. Here we review the Neolithic migrations of thin-tailed sheepand the later...
Tailoring fertilizer rates to catena positions improves nutrient use efficiency of rice in inland valleys of West Africa
Context Rainfed rice production in inland valleys has the potential to improve food security in West Africa, yet the average grain yield ranges only between 1 and 3 t ha−1. Increased nutrient use efficiency through site-specific fertilizer...